Buy 2-METHYL-AP-237 HCl Powder For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
What is 2-METHYL-AP-237 HCl Powder
2-METHYL-AP-237, chemically known as [1-2-methyl-4-(3-phenyl-2-propen-1-yl)-1-piperazinyl-1-butanone hydrochloride], is a synthetic opioid analgesic related to bucinnazine (AP-237). It contains a piperazine ring substituted with methyl and cinnamyl groups, acting as a mu-opioid receptor agonist with analgesic properties demonstrated in preclinical studies. This powder form, often offered as the hydrochloride salt, is a white crystalline solid used in pharmaceutical, forensic, and biochemical research for opioid receptor pharmacology and chemical characterization. It is strictly for research and forensic purposes and is not approved for human therapeutic or diagnostic use.
Technical Information of 2-METHYL-AP-237 HCl Powder
| Property | Detail |
|---|---|
| CAS No | 98608-59-4 |
| Alternate Names | 2-methyl AP-237, 2-methyl Buccinazine |
| Chemical Formula | C18H26N2O- HCl |
| Molecular Weight | 322.9 g/mol |
| Form | White crystalline powder |
| Purity | Typically >98% verified by chromatographic techniques |
| Solubility | Soluble in DMF (10 mg/mL), DMSO (15 mg/mL), ethanol (30 mg/mL), PBS pH 7.2 (10 mg/mL) |
| Melting Point | 211–213 °C |
| Storage Conditions | Store at -20°C, protect from light and moisture |
Typical Research Applications of 2-METHYL-AP-237 HCl Powder
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Mu-opioid receptor pharmacology and preclinical analgesic research
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Forensic analysis and toxicological profiling
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Analytical method development including HPLC and mass spectrometry
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Stability, solubility, and pharmacokinetic studies
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Structure-activity relationship studies of synthetic piperazine opioids
Safety and Handling Information for 2-METHYL-AP-237 HCl Powder
Handle exclusively in certified research laboratories with appropriate personal protective equipment. Avoid inhalation, ingestion, and skin contact. Dispose of all chemical waste according to regulatory guidelines.
Ordering & Shipping Summary for 2-METHYL-AP-237 HCl Powder
Available to licensed research facilities and institutions in accordance with regulatory requirements. Packaged with temperature and light protection measures to maintain chemical integrity.
Storage Conditions for 2-METHYL-AP-237 HCl Powder
Store in a tightly sealed container at -20°C in a dark, dry environment. Avoid exposure to light and moisture.
Alternatives to 2-METHYL-AP-237 HCl Powder
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Bucinnazine (AP-237)
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Other synthetic opioid piperazine derivatives
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Related synthetic analgesics
FAQ About 2-METHYL-AP-237 HCl Powder
Q: What is the primary activity of 2-methyl-AP-237?
A: It acts as a potent mu-opioid receptor agonist with analgesic properties.
Q: Is it approved for clinical use?
A: No, it is for research and forensic use only.
Q: What purity is typical?
A: Typically greater than 98%, confirmed by chromatographic analysis.
Q: How should it be stored?
A: At -20°C, protected from light and moisture.
Call to Action
Buy 2-METHYL-AP-237 HCl Powder for high-purity synthetic opioid research. Verified purity and precision dosing guarantee quality for laboratory and forensic studies.
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