O-DSMT Powder (O-Desmethyltramadol) For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
What is O-DSMT Powder
O-DSMT (O-Desmethyltramadol), also known as desmetramadol or M1, is the main active metabolite of tramadol. It functions as a potent μ-opioid receptor agonist, providing significantly stronger analgesic effects than the parent drug. In research contexts, O-DSMT powder is used for studying opioid pharmacology, analgesia mechanisms, metabolic pathways, and receptor binding characteristics. Its high purity powder form enables accurate dosing for preclinical studies.
Technical Information of O-DSMT Powder
| Property | Details |
|---|---|
| Chemical Name | 3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol |
| Molecular Formula | C15H23NO2 |
| Molecular Weight | 249.35 g/mol |
| CAS Number | 80456-81-1 |
| Physical Form | White to off-white crystalline powder |
| Purity | ≥98% research grade purity |
| Solubility | Soluble in water, ethanol, DMSO |
| Storage Conditions | Store in sealed containers in cool (2-8°C), dark, dry place |
Typical Research Applications
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Opioid receptor pharmacology and analgesic effect research
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Metabolic and pharmacokinetic profiling of tramadol metabolites
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Central nervous system studies on pain and nociception
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Toxicology and receptor binding mechanism investigations
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Pharmacodynamic analyses in preclinical models
Safety and Handling Information
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Use appropriate personal protective equipment including gloves and eye protection
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Conduct research in ventilated labs or fume hoods
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Avoid exposure via ingestion, inhalation, or skin contact outside approved protocols
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Dispose of all waste according to institutional safety regulations
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Exclusively for research purposes, not for human or veterinary use
Ordering & Shipping Summary
O-DSMT powder is supplied by certified vendors in secure, tamper-proof packaging. Shipment is regulated and limited to qualified research laboratories.
Storage Recommendations
Keep powder in airtight containers stored away from light, moisture, and heat at recommended temperatures (2–8°C) to ensure stability.
FAQ About O-DSMT Powder
Q: How potent is O-DSMT compared to tramadol?
A: O-DSMT is 2–4 times more potent and has a higher affinity for the μ-opioid receptor than tramadol.
Q: What purity level is typical?
A: Research-grade O-DSMT powder is typically ≥98% pure.
Q: What fields utilize O-DSMT?
A: Opioid receptor pharmacology, analgesic research, metabolism studies, and CNS pharmacodynamics.
Q: How should O-DSMT powder be stored?
A: In cool, dry, dark conditions in sealed containers to preserve integrity.
Call to Action
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